(i) Ph. D. thesis details (2009-2016)
- Title of the thesis: Spectroscopic and structural investigations on microwave synthesized nanostructured hydroxyapatite bioceramic materials
- University: Banaras Hindu University and Indian Institute of Technology (Banaras Hindu University)
- Supervisor: Prof. S. B. Rai (Department of Physics, Institute of Science, B.H.U.)
- Co-supervisor: Prof. D. Kumar (Department of Ceramic Engineering, Indian Institute of Technology-B.H.U.)
- Date of Ph.D. enrolment: 1st Sep. 2009
- Date of thesis submission: 15th April 2015
- Date of viva-voce exam: 17th Feb. 2016
- Date of issue of degree: 19th Feb. 2016
Work carried out/ learning
According to my synopsis of my PhD thesis, pure and doped hydroxyapatite nanoparticles and their composites have been prepared via microwave irradiation technique. Due to having very less yield of hydroxyapatite (HAp) as product material, I developed a technique in which a significant amount of the HAp was produced and yield was enhanced many folds. Effects of physical conditions such as temperature, and time duration etc as well as chemical conditions such as pH value, presence of dopant(s), and reagents on structural and spectroscopic properties of HAp formed via microwave irradiation technique were comprehensively studied and remarkable results were published in internationally high repute journals, J. Am. Ceram. Soc., JACOM, Ceram. Int., NJC (RSC), etc. During, my thesis tenure, I was also engaged in few other projects running in my working laboratories at the Department of Physics, Institute of Science and Department of Ceramic Engineering, Indian Institute of Technology, Banaras Hindu University. Apart from my synopsis bases work, I have also worked on glass and glass ceramics in collaboration with Department of Physics, university of Lucknow, on phytomedicines in collaboration with Department of Dravyaguna, Institute of medical Sciences, Banaras Hindu University as well as on missile technology/ rocket science in collaboration with the Department of Chemical Engineering, Indian Institute of Technology (BHU) and DRDO, GoI.
(C) Work experience in reverse-chronological order
(i) Assistant Professor (Physics): (2023- ongoing)
- Tenure: 24th August 2023 to ongoing.
- Designation: Assistant Professor of Physics,
- Host University: GLA University, Mathura U.P., India (NAAC Accredited A+) www.gla.ac.in
- Courses Taught: Physics in undergraduate (B.Sc.) postgraduate (M.Sc.) and B. Tech. classes
- Responsibilities: Teaching, Research and relevant assignments
- Additional Responsibility: Training and Placement Advisor, Department of Physics, GLA University, Mathura.
(ii) Principal at DPS, Gorakhpur: (2020- 2023) 3-Years
- Tenure: 11th August 2020 to 23rd Aug. 2023.
- Designation: Principal
- Host University: Delhi Public School, Gorakhpur https://www.dpsgorakhpur.co.in
- Courses Taught: Physics
- Responsibilities: Academic, Administrative, and Financial responsibilities
(iii) Awarded by Dr. D.S. Kothari Postdoctoral Fellowship (2021)
(iv) Assistant Professor (2019-2020) 1-Year
- Tenure: 7th August 2019 to 7th August 2020.
- Designation: Assistant Professor of Physics,
- Host University: Shri Venkateshwara University (SVU), Gajaraula, U.P., India www.svu.edu.in
- Courses Taught: Physics in undergraduate (B.Sc.) and postgraduate (M.Sc.) classes
- Other responsibilities: Held the responsibility of members in many universality level committees of academic administration.
(v) Postdoctoral Research Experience-I (2016-2018) 2- Years
- Tenure: 14th July 2016 to 13th July 2018 (2 years)
- Title of Project: Synthesis and characterizations of hydroxyapatite nano drug vehicles for effective drug delivery and their in-vitro/in-vivo studies in bone
- Mentor: Dr. Ritu Trivedi (Principal Scientist)
- Sanctioned Amount: Rs. 18, 70, 000/-
- Host Institute: CSIR-Central Drug Research Institute, Lucknow http://www.cdri.res.in/
- Role in Project: Principal Investigator (P.I.)
- Funding Agency: Science and Engineering Research Board (SERB), Government of India
(v) Postdoctoral Research Experience-I (2016-2018) 2- Years
- Tenure: 14th July 2016 to 13th July 2018 (2 years)
- Title of Project: Synthesis and characterizations of hydroxyapatite nano drug vehicles for effective drug delivery and their in-vitro/in-vivo studies in bone
- Mentor: Dr. Ritu Trivedi (Principal Scientist)
- Sanctioned Amount: Rs. 18, 70, 000/-
- Host Institute: CSIR-Central Drug Research Institute, Lucknow http://www.cdri.res.in/
- Role in Project: Principal Investigator (P.I.)
- Funding Agency: Science and Engineering Research Board (SERB), Government of India
- Work carried out/ learning: Successful synthesis of pure and doped hydroxyapatite nanoparticles and their composites. In order to ensure cytotoxicity, in-vitro cell viability test was performed for all the desired samples. Once samples qualify the cytotoxicity test, in-vitro osteogenic behavior was studied by Alakaline phosphatase (ALP) activity and biomineralization. For, in-vitro studies, osteoblast calvarial cells of rat/ mice pups were taken in use. The samples best performed in in-vitro studies were further preceded for in-vivo investigations using S.D. rat. In-vivo investigations of few selective samples used as scaffold/ implant/ injectable form confirmed the osteogenic potential of synthesized ceramic bioceramic based compositions.
D. Fellowship(s)/ Award(s): 5
- UGC-Dr. D.S. Kothari Postdoctoral Fellowship (DSK-PDF). 2021
- Best poster award in an “International Symposium on Advances in Functional & Biological Materials (ISAFBM- 2019)” held on 28th February, 2019 and Organized by Humboldt Academy Lucknow & Physics Department,
- University of Lucknow
- SERB-National-Postdoctoral Fellowship (N-PDF) 2016-2018
(a) Doctoral fellowship(s) availed during Ph. D. tenure (2009-2016)
- UGC-RFSMS-Senior Research Fellowship (SRF) 2014-2015
- UGC-RFSMS-Junior Research Fellowship (JRF) 2012-2014
- UGC-Research Fellowship 2009-2012
E. Teaching interest and highlights
I enjoy the teaching of Physics/ Applied Physics/ Engineering Physics at undergraduate (B.Sc./ B.E./ B. Tech) and postgraduate (M.Sc./ M.E./ M. Tech./ M.Phil./) levels of UGC/ AICTE approved syllabi and Ph.D. course work for Indian/ state/ deemed universities and institutes. I have learnt to develop my own teaching style with the following objectives:
- To ignite a passion for the scope of the subject.
- To internalize the fundamental concepts
- To make the students thirsty to look for more excitement and knowledge by themselves.
- To make students appreciate the essential professional standards one should follow in order to become a productive professional.
- The constant evaluation of the conversation in the classroom is of paramount importance to me.
F. Research Interest
Developing innovative biocomposites/ biomaterials based on Ca-P/ pure/ doped Hydroxyapatite (HAp) with potential osteogenic efficacy for bone scaffolds/ bone grafts/ bone and dental implant applications. My research interest includes the in-vitro/ in-vivo assessment of osteogenic efficacy of prepared biomaterials. Developing the HAp based bone replacement materials of excellent mechanical and biological properties. Study of osteogenic efficacy of materials/ derivatives and other compounds.
Research highlights/ technical skills/ handling with/ familiar with
- Synthesis of nanostructured hydroxyapatite and hydroxyapatite based biocomposites using microwave irradiation, hydrothermal, sol-gel and microwave sol-gel techniques.
- Materials Science, Biomaterials, Nanotechnology, Ceramic Engineering, Spectroscopy, Missile Technology
- Thermal analysis of materials using TG-DTA and DSC thermograms.
- Structural analysis of materials using XRD, SEM and TEM, XPS, EDX
- Spectroscopic analysis of materials using FT-IR, Raman and UV-Vis.
- Optical/laser analysis of materials using Laser based techniques viz. LIBS and PL (familiar).
- Rat/mice osteoblast calvarial cell culture and familiar with bone marrow and chondrocytes cell cultures
- MTT assay, ALP activity, biomineralization, and familiar with RT-PCR, confocal imaging & µ-CT
- Basic knowledge of M.S. Office and various scientific softwares viz. Origin, prism, JCPDS, etc.
I. Proceeding(s)/ Book chapter(s) 03
| S.N. |
Title |
Author(s) |
Journal/ Publisher |
Year/ Vol./ Page numbers |
| 1 |
Study of morphological behavior of hydroxyapatite, EDTA hydroxyapatite and metal doped EDTA hydroxyapatite synthesized by chemical co-precipitation method via hydrothermal route, |
Bhattacharjee B.N., Mishra V.K.,Rai S.B., Parkash O., *Kumar D., |
Key Engg. Mater. |
2016, 720, 210-214 |
| 2 |
Environmental friendly and fast formation of hydroxyapatite nanostructures: a potential material for coating on orthopedic implants and drug delivery applications |
Mishra VK, Kumar D., Sharma AK, Jha, P, Vikram K, Tripathi PK. |
Bentham Science Book |
2025 (Under review) |
| 3 |
Functional Properties of Discrete Nano-Scaled Materials |
Mishra VK,, Sharma AK, |
Bentham Science Book |
2025 (Under review) |
J. Projects reports/ thesis/ dissertations 02
- “Fabrication of chemically engineered 45S5 Bioglass® and its composites with biometallic alloy powder to enhance its osteogenic activities and machinability for bone implant and prosthodontic applications: 2021 by University Grant Commission (UGC), New Delhi, Government of India in form of Dr. D.S. Kothari Postdoctoral Fellowship.
- Project on ‘Synthesis and characterizations of hydroxyapatite nano drug vehicles for effective drug delivery and their in-vitro/ in-vivo studies in bone ’is sanctioned in 2016 by Science and Engineering Research Board (SERB), Department of Science and Technology (DST), Government of India to carry out postdoctoral research. Sanctioned cast of project was INR 19,20,000/- (Major Project)
Ph.D./ thesis (being) supervised
- One Research scholar is working on “Biomaterials” to earn his Ph.D. degree